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pubmed-article:6662193pubmed:abstractTextThe inhibitory effects of ketanserin and spiroperidol (a neuroleptic drug) on the contractile response of isolated rat uterus to serotonin (5-HT) were investigated. Ketanserin caused non-competitive inhibition of the contractile response to 5-HT and showed more selective inhibition than the other 5-HT antagonists tested. The inhibitory effect of spiroperidol was comparable with the effects of classical 5-HT antagonists. These results suggest that ketanserin and spiroperidol selectively inhibit the contractile response of isolated rat uterus to 5-HT.lld:pubmed
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pubmed-article:6662193pubmed:articleTitleSelective inhibition by ketanserin and spiroperidol of 5-HT-induced myometrial contraction.lld:pubmed
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