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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1-2
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|
pubmed:dateCreated |
1984-3-2
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|
pubmed:abstractText |
The inhibitory effects of ketanserin and spiroperidol (a neuroleptic drug) on the contractile response of isolated rat uterus to serotonin (5-HT) were investigated. Ketanserin caused non-competitive inhibition of the contractile response to 5-HT and showed more selective inhibition than the other 5-HT antagonists tested. The inhibitory effect of spiroperidol was comparable with the effects of classical 5-HT antagonists. These results suggest that ketanserin and spiroperidol selectively inhibit the contractile response of isolated rat uterus to 5-HT.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0014-2999
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
9
|
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pubmed:volume |
96
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
155-8
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|
pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:6662193-Animals,
pubmed-meshheading:6662193-Butyrophenones,
pubmed-meshheading:6662193-Estradiol,
pubmed-meshheading:6662193-Female,
pubmed-meshheading:6662193-Ketanserin,
pubmed-meshheading:6662193-Ovary,
pubmed-meshheading:6662193-Piperidines,
pubmed-meshheading:6662193-Rats,
pubmed-meshheading:6662193-Rats, Inbred Strains,
pubmed-meshheading:6662193-Serotonin Antagonists,
pubmed-meshheading:6662193-Spiperone,
pubmed-meshheading:6662193-Uterine Contraction
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|
pubmed:year |
1983
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|
pubmed:articleTitle |
Selective inhibition by ketanserin and spiroperidol of 5-HT-induced myometrial contraction.
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pubmed:publicationType |
Journal Article
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