Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1984-1-7
pubmed:abstractText
Bioavailability of chloramphenicol pharmaceutical forms prepared with the use of antibiotic substances differing in their dispersion levels was studied. It was shown that the level and rate of the drug absorption into blood did not always depend on the size of the substance particles. Fine crystalline substances of the antibiotic manufactured by two firms almost not differing in their dispersion levels markedly differed in the rate of antibiotic transfer into solution and the level of its blood absorption in humans. Tablets prepared with the use of the above substances were also characterized by various bioavailability levels. Study of the dissolution rate of separate fractions of the same substance revealed dependence of this parameter on the particle size.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0003-5637
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
751-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Bioavailability of levomycetin preparations for oral use].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract