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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1984-1-7
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pubmed:abstractText |
Twenty consecutive patients who had biopsy proven metastatic colorectal cancer were treated with combination chemotherapy. The drug regimen (FVH), in a 4 week cycle, consisted of 5-fluorouracil (600 mg/m2 i.v. on days 1, 8, 15 and 22), vincristine (1.4 mg/m2 i.v. on day 4), and hydroxyurea (2400 mg/m2 p.o. on days 3, 10, 17 and 24). Three of the 18 evaluable patients achieved an objective tumor remission (2 CR and 1 PR) and 15 patients had stable disease. The overall response rate to FVH was therefore not superior to that achieved in patients who received 5-fluorouracil alone, and the overall survival in this study was comparable to that of other studies involving patients with metastatic colorectal cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0300-8916
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
31
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
485-7
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pubmed:dateRevised |
2008-12-12
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pubmed:meshHeading |
pubmed-meshheading:6649073-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:6649073-Colonic Neoplasms,
pubmed-meshheading:6649073-Female,
pubmed-meshheading:6649073-Fluorouracil,
pubmed-meshheading:6649073-Humans,
pubmed-meshheading:6649073-Hydroxyurea,
pubmed-meshheading:6649073-Male,
pubmed-meshheading:6649073-Middle Aged,
pubmed-meshheading:6649073-Neoplasm Metastasis,
pubmed-meshheading:6649073-Rectal Neoplasms,
pubmed-meshheading:6649073-Vincristine
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pubmed:year |
1983
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pubmed:articleTitle |
5-Fluorouracil, vincristine and hydroxyurea combination chemotherapy in metastatic colorectal cancer.
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pubmed:publicationType |
Journal Article
|