Linked Life Data

6644821

Source:http://linkedlifedata.com/resource/pubmed/id/6644821

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-1-7
pubmed:abstractText
Striking ultrastructural and hormonal parameters of premature menopause and aging are reported in female Xyleborus ferrugineus fed cholesterol, rather than 7-dehydrocholesterol, as a sole dietary sterol. The titer of free ecdysteroids in such 63-day-old females remained abnormally elevated through the period of the ovarian cycle. A similar plateauing of such elevated titer also occurred in 147-day-old, irregularly cycling females fed only cholesterol as the dietary sterol. These hormonal changes in menopausing X. ferrugineus females seem especially analogous to the maintenance of an elevated concentration of 17-beta-estradiol through the estrous, as well as the proestrous, ovary of aged irregularly cycling rats. The highly abnormal ultrastructure of ovaries of X. ferrugineus females aged 216 days on a diet containing cholesterol as the sole sterol seems quite analogous to that of the nonovulatory follicles in older, irregularly cycling rats. Our new findings involving aging X. ferrugineus females indicate further the usefulness of an insect model to study aging processes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0362-2525
pubmed:author
pubmed:issnType
Print
pubmed:volume
177
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-54
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Changes in ovarian ultrastructure and ecdysteroid titer during the aging process of female Xyleborus ferrugineus (Coleoptera: Scolytidae).
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't