rdf:type |
|
lifeskim:mentions |
umls-concept:C0014792,
umls-concept:C0023175,
umls-concept:C0033733,
umls-concept:C0034693,
umls-concept:C0036884,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1880497,
umls-concept:C1996904,
umls-concept:C2911692
|
pubmed:issue |
4
|
pubmed:dateCreated |
1978-8-14
|
pubmed:abstractText |
Following oral administration of lead a difference in free erythrocyte protoporphyrin (FEP) increase was found between adult male, adult female and suckling rats: young animals are more susceptible than adult female rats which in turn exhibit a greater FEP increase than adult male animals. This observation parallels that made previously in humans. Possible difference in iron metabolism does not appear to explain the sex-linked difference in FEP response to lead. Sex hormones mainly progesterone, seem to play a role but their interaction with lead on the FEP response is restricted to female rats and apparently is not mediated through changes in delta-aminolevulinic acid synthetase activity.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0300-483X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
361-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:663944-Age Factors,
pubmed-meshheading:663944-Animals,
pubmed-meshheading:663944-Castration,
pubmed-meshheading:663944-Erythrocytes,
pubmed-meshheading:663944-Estradiol,
pubmed-meshheading:663944-Female,
pubmed-meshheading:663944-Gonadal Steroid Hormones,
pubmed-meshheading:663944-Iron,
pubmed-meshheading:663944-Lead Poisoning,
pubmed-meshheading:663944-Male,
pubmed-meshheading:663944-Porphyrins,
pubmed-meshheading:663944-Pregnancy,
pubmed-meshheading:663944-Progesterone,
pubmed-meshheading:663944-Protoporphyrins,
pubmed-meshheading:663944-Rats,
pubmed-meshheading:663944-Sex Factors,
pubmed-meshheading:663944-Testosterone
|
pubmed:year |
1978
|
pubmed:articleTitle |
Influence of sex hormones on free erythrocyte protoporphyrin response to lead in rats.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|