Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1983-12-20
pubmed:abstractText
Decreased lung clearance of Staphylococcus aureus has been reported in mice homozygous for the cribriform degeneration (cri) autosomal recessive mutation. In the present study, the phagocytic capacities of alveolar and peritoneal macrophages were quantitated by applying kinetics of the first order reaction criteria. The characteristics of the pulmonary and peritoneal mononuclear cell populations from mutant and control mice were indistinguishable. The kinetic assays revealed decreased phagocytosis work in both alveolar and peritoneal macrophages from cri/cri mice. The results lend support to this mutation as a possible model system to study the early stages of lung disease physiopathology in cystic fibrosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0090-0877
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
375-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Defective mononuclear phagocytic function in mice homozygous for the cribriform degeneration autosomic recessive mutation.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't