Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1983-11-23
|
pubmed:abstractText |
A mathematical description of the dose-response curve of heparin to the activated coagulation time is applied retrospectively to 20 patients treated with continuous heparin infusion. The adjusted heparin dose was compared with a calculated prediction using the theoretical mathematical model. The main actual dose was 28 U/kg/h, and the mean predicted dose was 25.8 U/kg/h. The correlation coefficient was 0.862 (p3 0.05). These data are used to develop a dosing adjustment chart. Special considerations prior to using the calculation or dosing adjustment chart are discussed. The use of this model may allow the clinician to determine more rapidly a therapeutic heparin dosage than previous empiric approaches.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0012-6578
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
632-4
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:6617481-Adult,
pubmed-meshheading:6617481-Blood Coagulation Tests,
pubmed-meshheading:6617481-Female,
pubmed-meshheading:6617481-Heparin,
pubmed-meshheading:6617481-Humans,
pubmed-meshheading:6617481-Male,
pubmed-meshheading:6617481-Middle Aged,
pubmed-meshheading:6617481-Pulmonary Embolism,
pubmed-meshheading:6617481-Thromboembolism,
pubmed-meshheading:6617481-Thrombophlebitis,
pubmed-meshheading:6617481-Whole Blood Coagulation Time
|
pubmed:year |
1983
|
pubmed:articleTitle |
Adjusting heparin infusion rates from the initial response to activated coagulation time.
|
pubmed:publicationType |
Journal Article
|