Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-7-27
pubmed:abstractText
Positron emission tomography is capable of making measurements of the permeability--surface-area (PS) product of the blood-brain barrier, if modeling constraints can be met. A strategy for measuring the PS product of ammonia is presented that can be applied to any compound that is taken up by the brain and trapped before back-diffusion occurs. A second strategy for measuring the PS product of compounds that are not metabolically trapped is also presented. The flexibility of positron emission tomography and the variety of appropriately labeled compounds suggest that this technique will be very important in the characterization of the blood-brain barrier in humans in health and in disease.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0364-5134
pubmed:author
pubmed:issnType
Print
pubmed:volume
15 Suppl
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S103-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Functional evaluation of the blood-brain barrier using positron emission tomography.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.