Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-6-11
pubmed:abstractText
In vertebrate visual cells, cytoplasmic organelles are degraded within autophagic vacuoles occurring in inner segments. In isolated frog retinas in vitro, an increase of autophagic activity as compared to in vivo controls was observed and a reduction of autophagic activity in dim red light as compared to bright white light (Remé, 1981). In this study, isolated frog retinas were superfused: (a) with and without serum addition to the superfusion medium at 400 1 X illumination; (b) without serum at 400 1 X fluorescent light or without visible light. Autophagy was significantly decreased, in cones more than in rods, in retinas superfused with serum containing medium and superfused without visible light. The increased autophagy in serum free medium is interpreted to provide precursor molecules for protein synthesis. The reduction of autophagy in darkness may reflect different functional and metabolic states of visual cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0012-4486
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
377-83
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Modification of autophagic degradation by medium- and illumination conditions in frog visual cells in vitro.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro