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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-2-24
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pubmed:abstractText |
Radio-calcium absorption, plasma 25-hydroxyvitamin D [25-(OH)D] and 1,25-dihydroxyvitamin D [1,25-(OH)2D] concentrations were measured in 19 elderly women with, and 21 without, vertebral fractures, before and after treatment with 25-hydroxyvitamin D3 [25-(OH)D3], to establish whether malabsorption of calcium in elderly women with vertebral fractures has a cause different from that in elderly women without vertebral fractures. Malabsorption of calcium and low plasma 25-(OH)D and 1,25-(OH)2D concentrations were common in both groups of women but there was no significant difference in these variables between the two groups. After treatment with 40 micrograms of 25-(OH)D3 daily for 7 days, there was a significant increase in plasma 25-(OH)D and 1,25-(OH)2D in both groups of women, but radio-calcium absorption increased significantly only in the group without vertebral fractures. Elderly women with vertebral fractures have malabsorption of calcium which is resistant to the action of vitamin D metabolites at concentrations which correct calcium malabsorption in elderly women without vertebral fractures.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1,25-dihydroxyergocalciferol,
http://linkedlifedata.com/resource/pubmed/chemical/25-Hydroxyvitamin D 2,
http://linkedlifedata.com/resource/pubmed/chemical/Calcifediol,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Ergocalciferols
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0143-5221
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
103-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6606522-25-Hydroxyvitamin D 2,
pubmed-meshheading:6606522-Aged,
pubmed-meshheading:6606522-Calcifediol,
pubmed-meshheading:6606522-Calcium,
pubmed-meshheading:6606522-Calcium Radioisotopes,
pubmed-meshheading:6606522-Ergocalciferols,
pubmed-meshheading:6606522-Female,
pubmed-meshheading:6606522-Fractures, Spontaneous,
pubmed-meshheading:6606522-Humans,
pubmed-meshheading:6606522-Intestinal Absorption,
pubmed-meshheading:6606522-Middle Aged,
pubmed-meshheading:6606522-Osteoporosis,
pubmed-meshheading:6606522-Spinal Injuries
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pubmed:year |
1984
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pubmed:articleTitle |
Calcium malabsorption in elderly women with vertebral fractures: evidence for resistance to the action of vitamin D metabolites on the bowel.
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pubmed:publicationType |
Journal Article
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