Linked Life Data

6604510

Source:http://linkedlifedata.com/resource/pubmed/id/6604510

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-10-28
pubmed:abstractText
The examination of patients with Myasthenia gravis revealed that before thymectomy the number of T and B cells in the peripheral blood did not deviate from the norm. It was also observed that their sera contained factor stimulating T lymphocytes to the spontaneous rosette formation, theta antigen generation in xynogeneic system and hydrocortisone-resistant thymocytes. No factor inhibiting the spontaneous rosette formation by T lymphocytes or causing the transmission from Thy-1.2+ cells to Thy-1.2-cells was detected in these sera. Thymectomy resulted in the immediate fall of T lymphocytes number in the peripheral blood of the patients examined. Besides, serum of most patients almost totally lost the stimulating factor. The fall of T cells number did not involve the appearance of the inhibitory factor in the patients' serum. Different than in others results gave blood and serum analysis in the patient tymectomized 10 years earlier. Her blood contained the normal number of T and B lymphocytes and the stimulatory factor of a "limited" activity. It displayed only the ability of generating hydrocortisone-resistant cells, it appeared nonactive in generating theta antigen or restoring the ability of rosette formation by T cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-069X
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
T lymphocytes modifying factors in sera of patients with Myasthenia gravis.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't