Linked Life Data

6603253

Source:http://linkedlifedata.com/resource/pubmed/id/6603253

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1983-9-23
pubmed:abstractText
Cholinergic enzyme activity was investigated over the course of spinal cord development from early larval (tadpole) stages to adult life in bullfrogs (Rana catesbeiana). Acetylcholinesterase (AChE) activity examined histochemically in spinal neurons and AChE and choline acetyltransferase (ChAT) activities were measured biochemically in axons of developing hindlimb motoneurons. At early larval stages, only spinal neurons born during embryonic life (primary neurons) showed histochemical evidence of AChE activity. Hindlimb motoneuron somata did not show AChE activity until mid-larval stages. AChE and ChAT activities were found in hindlimb motoneuron axons at the earliest stages examined, when the hindlimb consists of a small bud of undifferentiated mesenchyme. Activities of both enzymes show steady increases over the course of development until climax, when activities maintain a plateau until metamorphosis is complete. Total activities of both enzymes increase as the adult frog grows, although ChAT activity shows a much greater proportional increase than AChE activity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:volume
284
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
275-82
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Cholinergic enzyme activity in neurons of the developing anuran spinal cord.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.