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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1983-5-27
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pubmed:abstractText |
Twenty-two patients with newly diagnosed acute myelocytic leukemia (AML) and white cell counts (WBC) greater than 100,000/microliters received one, two, or three leukaphereses prior to induction chemotherapy with cytosine arabinoside (Ara-C) and daunorubicin (DNR). Fifteen of 22 (68%) achieved a complete remission. Greater than a 30% decrease in initial WBC was found to be an important predictor of response. Fifteen of 17 patients (88%) with greater than 30% reduction of initial WBC achieved remission, while none of 5 patients with less than a 30% reduction responded (P = 0.001).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0098-1532
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
76-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6572782-Adolescent,
pubmed-meshheading:6572782-Adult,
pubmed-meshheading:6572782-Aged,
pubmed-meshheading:6572782-Child,
pubmed-meshheading:6572782-Cytarabine,
pubmed-meshheading:6572782-Daunorubicin,
pubmed-meshheading:6572782-Drug Therapy, Combination,
pubmed-meshheading:6572782-Humans,
pubmed-meshheading:6572782-Leukapheresis,
pubmed-meshheading:6572782-Leukemia, Myeloid, Acute,
pubmed-meshheading:6572782-Leukocyte Count,
pubmed-meshheading:6572782-Leukocytosis,
pubmed-meshheading:6572782-Middle Aged
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pubmed:year |
1983
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pubmed:articleTitle |
Therapeutic leukapheresis for hyperleukocytosis in acute myelocytic leukemia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|