Linked Life Data

6548902

Source:http://linkedlifedata.com/resource/pubmed/id/6548902

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1984-12-31
pubmed:abstractText
We studied four cases of collagenous colitis (CC), which is characterized by thickening of the subepithelial collagenous layer of the colorectal mucosa and is associated with chronic watery diarrhea. Eighteen cases of CC have been previously reported in the literature, to our knowledge. In our four patients, ultrastructural study and collagen immunotyping demonstrated that the basement membrane over the thickened collagen was normal. We found no similar collagenous thickening in a series of 96 biopsy specimens of chronic inflammatory bowel diseases, but collagenous thickening was noted in 17 (25%) of 68 colonic metaplastic polyps. The cause of CC is unknown. The pericryptal fibroblastic sheath of the colonic mucosa has a probable role in the development of CC and metaplastic polyps. The role of the numerous mast cells present in our four cases of CC is currently unknown.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-9985
pubmed:author
pubmed:issnType
Print
pubmed:volume
108
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
977-82
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Collagenous colitis. Ultrastructural study and collagen immunotyping of four cases.
pubmed:publicationType
Journal Article, Comparative Study, Case Reports