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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1985-4-26
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pubmed:databankReference | |
pubmed:abstractText |
A recombinant lambda Charon 4A bacteriophage, D alpha G-1, carrying the genes coding for the duck embryonic (pi') and adult (alpha A, alpha D) alpha-like globins was isolated from a previously constructed duck DNA recombinant library. The three globin genes are transcribed from the same DNA strand and are arranged in the order of their expression during development: 5'-pi'-alpha D-alpha A-3'. We have determined the complete nucleotide sequence of the duck pi'-globin gene, including the flanking regions. Due to the unusual length of intron 1 (963 bp) and intron 2 (568 bp) the 2167-bp duck pi'-globin gene is by far the largest among all known mammalian or avian alpha- and beta-globin genes. For instance, the duck pi'-globin gene introns are almost twice as long as those of the chicken pi'-globin genes. A surprisingly high degree of nucleotide sequence homology (88%) has been found for the 5' flanking region (positions -1 to -223) of the duck and chicken pi'-globin gene.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6530142-Amino Acid Sequence,
pubmed-meshheading:6530142-Animals,
pubmed-meshheading:6530142-Base Sequence,
pubmed-meshheading:6530142-Chickens,
pubmed-meshheading:6530142-Chromosome Mapping,
pubmed-meshheading:6530142-Cloning, Molecular,
pubmed-meshheading:6530142-DNA, Recombinant,
pubmed-meshheading:6530142-Ducks,
pubmed-meshheading:6530142-Genes,
pubmed-meshheading:6530142-Globins,
pubmed-meshheading:6530142-Species Specificity
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pubmed:year |
1984
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pubmed:articleTitle |
Chromosomal arrangement of the duck alpha-globin genes and primary structure of the embryonic alpha-globin gene pi.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|