Linked Life Data

6529779

Source:http://linkedlifedata.com/resource/pubmed/id/6529779

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-5-14
pubmed:abstractText
Tritiated rifaximin was administered in a single oral dose of 10 mg/kg (specific activity 8.998 microCi/mg) and 100 mg/kg (specific activity 0.786 microCi/mg) to rats. After treatment, at fixed times, the animals were sacrificed and the radioactivity in plasma, urine, feces, and in the principal organs and tissues was measured. The radioactivity present in the feces of the two groups of rats was more than 95% of the administered dose, while the amounts found in the urine ranged between 1.15% and 1.5% of the dose. In the plasma and tissues the radioactivity levels were very low. This evidence confirmed the scanty gastroenteric absorption of L/105. Furthermore, as the radioactivity levels maintained almost the same value during the trial, there was the possibility that the amounts found were in part due to isotopic exchange between tritium of 3H-L/105 and hydrogen of water.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0392-906X
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
373-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Rifaximin (L/105), a new topical intestinal antibiotic: pharmacokinetic study after single oral administration of 3H-rifaximin to rats.
pubmed:publicationType
Journal Article