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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1978-7-24
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pubmed:abstractText |
The lateral cerebroventricle was perfused using two different labelling procedures in three separate experiments on 5-hydroxytryptamine metabolism. The sensitivity of 5-hydroxytryptamine metabolism to various drugs was subsequently determined. The results demonstrate that two serotonin reuptake blockers, imipramine and fluoxetine, increase the efflux of 3h-5-hydroxytryptamine into the ventricle without affecting the efflux of 3H-5-hydroxyindoleacetic acid. BL-3912 A, a drug with weak serotonin agonist activity, also increased the efflux of 3H-5-hydroxytryptamine into the ventricle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0091-3057
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:652825-Animals,
pubmed-meshheading:652825-Cerebral Ventricles,
pubmed-meshheading:652825-Chromatography, Thin Layer,
pubmed-meshheading:652825-Female,
pubmed-meshheading:652825-Hydroxyindoleacetic Acid,
pubmed-meshheading:652825-Imipramine,
pubmed-meshheading:652825-Injections, Intraventricular,
pubmed-meshheading:652825-Male,
pubmed-meshheading:652825-Rats,
pubmed-meshheading:652825-Serotonin,
pubmed-meshheading:652825-Time Factors,
pubmed-meshheading:652825-Tryptophan
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pubmed:year |
1978
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pubmed:articleTitle |
Synthesis and turnover of 3H-5-hydroxytryptamine in the later cerebroventricle.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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