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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1985-4-9
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pubmed:abstractText |
A group of long chain alpha, omega-diols (C29 to C34) has been identified in the lipids of steer and human meibomian gland excreta (meibum). These new lipids were isolated from the steer meibum unsaponifiables. Proof of structure was provided by 1) the column chromatographic behavior and TLC of the diols and their diacetates; 2) GLC on glass capillary columns; 3) fragmentation patterns in GC-MS; 4) NMR data, and 5) ozonolysis studies of the unsaturates. Chain types for the steer sample were 51% straight monoenes, 8.5% straight saturates, 39% iso and anteiso saturates and 1.5% iso and anteiso unsaturates. GC for the human sample gave straight monoenes 83%, straight saturates 8%, and iso plus anteiso saturates 9%. Close correspondence of the alpha, omega-diol chain lengths and types with meibum omega-hydroxy fatty acids suggests a biochemical precursor relationship.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0024-4201
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
990-3
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6527617-Animals,
pubmed-meshheading:6527617-Castration,
pubmed-meshheading:6527617-Cattle,
pubmed-meshheading:6527617-Chromatography, Thin Layer,
pubmed-meshheading:6527617-Eye,
pubmed-meshheading:6527617-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:6527617-Glycols,
pubmed-meshheading:6527617-Humans,
pubmed-meshheading:6527617-Male,
pubmed-meshheading:6527617-Sebaceous Glands,
pubmed-meshheading:6527617-Species Specificity
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pubmed:year |
1984
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pubmed:articleTitle |
The occurrence of long chain alpha, omega-diols in the lipids of steer and human meibomian glands.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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