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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1985-1-17
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pubmed:abstractText |
The rate of penetration of fluorescein and gentamicin ions into the anterior chamber of the rabbit was increased more than 100-fold by the passage of 1 mamp; the amount of drug that penetrates is better controlled by iontophoresis than by instillation. The potential value, the safety and the limitations of this procedure are discussed, and a theoretical basis for the increase is provided. Practical methods of using iontophoresis in the clinic are described. A 30-s application should result in a therapeutic level of the antibiotic in the anterior segment over a 12-hour period in eyes with an intact epithelium.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0003-9950
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1825-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6508622-Animals,
pubmed-meshheading:6508622-Anterior Chamber,
pubmed-meshheading:6508622-Aqueous Humor,
pubmed-meshheading:6508622-Cornea,
pubmed-meshheading:6508622-Female,
pubmed-meshheading:6508622-Fluorescein,
pubmed-meshheading:6508622-Fluoresceins,
pubmed-meshheading:6508622-Gentamicins,
pubmed-meshheading:6508622-Humans,
pubmed-meshheading:6508622-Iontophoresis,
pubmed-meshheading:6508622-Models, Theoretical,
pubmed-meshheading:6508622-Permeability,
pubmed-meshheading:6508622-Rabbits,
pubmed-meshheading:6508622-Risk
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pubmed:year |
1984
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pubmed:articleTitle |
A fresh look at iontophoresis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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