Linked Life Data

6508227

Source:http://linkedlifedata.com/resource/pubmed/id/6508227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-1-3
pubmed:abstractText
Three procedures have been compared for monitoring heparin in patients undergoing cardiopulmonary bypass: (1) activated clotting time (ACT) (2) protamine titration, and (3) fluorometric substrate assay. The ACT monitors the degree of anticoagulation. It is easy to perform and is relatively inexpensive, however, it does not correlate well with heparin levels and may not accurately predict the protamine dose for neutralization of heparin at the completion of bypass. A protamine titration assay or an assay using a thrombin-sensitive fluorometric substrate measures the heparin level and calculates the protamine requirement at the completion of surgery; however, these assays do not indicate the degree of anticoagulation. The fluorometric assay is the less expensive of the two assay measuring heparin, but it requires an experienced technologist to perform the test.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0091-7370
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
474-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Heparin monitoring during cardiopulmonary bypass.
pubmed:publicationType
Journal Article, Comparative Study