Linked Life Data

6493631

Source:http://linkedlifedata.com/resource/pubmed/id/6493631

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
1984-12-20
pubmed:abstractText
The effect of verapamil, a calcium-entrance blocker, on K+-evoked release of endogenous dopamine from tuberoinfundibular neurons incubated in vitro was studied. This compound, added to the incubation medium, at the dose of 10(-6) M, significantly reinforced K+-induced dopamine release, whereas, at higher doses (10(-5), 5 X 10(-5) and 10(-4) M), it completely prevented the stimulated dopamine release. The results obtained with the higher doses showed the calcium dependence of K+-evoked release of endogenous dopamine from central neurons. The opposite effect, seen with the lower dose of verapamil, could be due to different pharmacological properties of the drug.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Dual effect of verapamil on K+-evoked release of endogenous dopamine from arcuate nucleus-median eminence complex.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't