Linked Life Data

6492890

Source:http://linkedlifedata.com/resource/pubmed/id/6492890

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-11-23
pubmed:abstractText
The effect of the oral administration of 0.150 mg/m2 clonidine on the plasma level of human growth hormone (hGH) was studied in 53 adults (25 males and 28 females) aged from 28 to 68 years, of which 15 were healthy volunteers and 38 were hypertensive. Both the normal and hypertensive subjects of both sexes showed an age-related responsiveness of hGH to clonidine, with a normal or partial response in the younger subjects and blunting or lack of response in the more elderly subjects. In the females the blunting of the hGH response appeared at an earlier age than in the males. It is speculated that an alteration in the sensitivity of the central alpha-adrenergic receptors and a decrease in the sex steroid hormones may account for the progressive reduction in hGH secretion with advancing age.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0047-6374
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-100
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Effect of aging on human plasma growth hormone response to clonidine.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't