Linked Life Data

6469424

Source:http://linkedlifedata.com/resource/pubmed/id/6469424

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1984-10-17
pubmed:abstractText
Results of animal experiments indicate that indomethacin has a marked inhibitory effect on the activity of the hepatic microsomal mixed function monooxygenase (MFO) enzyme system. In order to verify this effect of indomethacin in humans, the authors studied antipyrine kinetics and D-glucaric acid excretion in 14 patients before and after 7 days treatment with two different doses of the drug. In contrast to the results obtained from animal experiments, there was no change in the activity of MFO in man. This can possibly be explained by species difference.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0174-4879
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
353-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Effect of a non-steroid anti-inflammatory agent on the drug metabolizing activity of the human liver.
pubmed:publicationType
Journal Article