Linked Life Data

6465677

Source:http://linkedlifedata.com/resource/pubmed/id/6465677

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-9-5
pubmed:abstractText
Serum fibronectin concentration was measured by immunoelectrophoresis in rats exposed to 1 atmosphere absolute (ata) of oxygen for 24 to 72 h and at 30-min intervals during 1 to 5 h of exposure to 4 ata O2. At 1 ata O2, there was a progressive increase in serum fibronectin, which became significant at 48 h and was 2.5 times the control value by 72 h (p less than 0.01). At 4 ata O2, the rise in serum fibronectin was significant at 2 h, and was followed by an accelerated rate of increase to 5 h, at which time serum fibronectin concentration was 1.75 times the control value (p less than 0.05). By SDS-polyacrylamide gel electrophoresis and crossed immunoelectrophoresis, there was no evidence of fragmentation of fibronectin. This study demonstrated a progressive increase in serum fibronectin in the oxygen-exposed rat. The magnitude and course of the increase suggest increased synthesis and secretion of intact fibronectin molecules.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
130
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-41
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Serum fibronectin is elevated during normobaric and hyperbaric oxygen exposure in rats.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.