Linked Life Data

6442551

Source:http://linkedlifedata.com/resource/pubmed/id/6442551

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-5-17
pubmed:abstractText
Schistosoma haematobium eggs were recovered in urine from schoolchildren in Mwachinga Village, Kwale District, Kenya. The surface of the eggs showed a pattern similar to that observed in a circumoval precipitin (COP) test. Observed precipitates were removed by treatment of the eggs with pepsin, but were not affected by trypsin. Similar precipitates occurred after incubating the pepsin-treated eggs with urine supernatants from the same children. Attempts were made to identify the components that might contribute to observed bleb (precipitate) formation. The fluorescent antibody test revealed both IgG and IgM in the precipitate, while urine examination by immunodiffusion revealed IgG, IgM, IgA and C3. These components probably participated in the bleb formation. This possibility seemed more likely because of the presence of anti-egg antibodies in the immunoglobulins identified in the urine, and agrees well with the expected activity of pepsin on these immunoglobulins. These results, therefore, suggest that S. haematobium eggs recovered in urine contain precipitates formed mainly by immunoglobulins; it is necessary to treat such eggs with pepsin before carrying out a COP test. The relevance of these findings to the immunodiagnosis of Schistosomiasis haematobium in man is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-4983
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
627-32
pubmed:dateRevised
2009-5-18
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Precipitates found around Schistosoma haematobium eggs from human urine prior to circumoval precipitin test.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't