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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1984-11-14
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pubmed:abstractText |
Lesion-induced dopaminergic supersensitivity was investigated in 4-, 10-, and 28-month-old C57BL/6J mice. Apomorphine-induced rotational behavior was examined 5, 10, and 20 days after destruction of the dopamine-containing nigro-striatal pathway by intrastriatal infusion of 6-OHDA. No major differences between ages were observed in the extent or rate of development of contralateral rotation. It is concluded that age-differences in dopaminergic supersensitization are dependent upon the nature and/or severity of the sensitizing stimulus.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
308
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
333-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6434153-Aging,
pubmed-meshheading:6434153-Animals,
pubmed-meshheading:6434153-Corpus Striatum,
pubmed-meshheading:6434153-Dopamine,
pubmed-meshheading:6434153-Functional Laterality,
pubmed-meshheading:6434153-Hydroxydopamines,
pubmed-meshheading:6434153-Mice,
pubmed-meshheading:6434153-Mice, Inbred C57BL,
pubmed-meshheading:6434153-Motor Activity,
pubmed-meshheading:6434153-Oxidopamine,
pubmed-meshheading:6434153-Rotation,
pubmed-meshheading:6434153-Substantia Nigra
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pubmed:year |
1984
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pubmed:articleTitle |
Lesion-induced DA supersensitivity in aging C57BL/6J mice.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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