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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1984-6-26
|
| pubmed:abstractText |
The production of gamma-interferon (IFN gamma) in human peripheral blood T lymphocytes was induced by stimulation with PHA. For identification of the producer cell of IFN gamma, double fluorescence studies were undertaken and titers of interferon were determined in preparatively separated T-cell subpopulations reactive with one of the monoclonal antibodies OKT3, OKT4, OKT8, and OKIal . Production of IFN gamma was found in OKT3+, OKT4+, and OKT8+ cells. However, IFN gamma production occurred only in T cells also reactive with the monoclonal antibody OKIal . Addition of macrophages had no substantial effect on interferon titers in these subpopulations. It is suggested that the T cell subset producing IFN gamma is characterized by its reactivity with the monoclonal antibodies OKT3, OKT4 or OKT8, and OKIal .
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0014-4827
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
152
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
348-56
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading | |
| pubmed:year |
1984
|
| pubmed:articleTitle |
la-positive T lymphocytes are the producer cells of interferon gamma.
|
| pubmed:publicationType |
Journal Article
|