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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-6-18
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pubmed:abstractText |
A 68 000-Mr protein is a major component of a Nonidet P-40-insoluble fraction of lymphocyte plasma membrane prepared from human B lymphoblastoid cells ( BRI 8) and pig mesenteric lymph nodes. The association of the protein with the detergent-insoluble complex depends on free Ca2+ concentrations of greater than 10 microM. The human and pig 68 000-Mr proteins were purified and appear to be homologous on the basis of amino acid composition and peptide mapping. The protein is monomeric, has pI 5.8 and a single high-affinity Ca2+-binding site (KD 1.2 microM). The results are discussed in terms of the possible role of the 68 000-Mr protein as an intracellular Ca2+ receptor in lymphocytes.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-103459,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-14907713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-158957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-227246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-236308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-274701,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-320200,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-4611687,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-4626639,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-4773289,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-4853690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-492320,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-558885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6172996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6212650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6250447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6453651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6721859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6757171,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6893051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6893424,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-6893854,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/6426470-962102
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0264-6021
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
219
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
309-16
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6426470-Amino Acids,
pubmed-meshheading:6426470-Animals,
pubmed-meshheading:6426470-Annexin A6,
pubmed-meshheading:6426470-Calcium-Binding Proteins,
pubmed-meshheading:6426470-Cell Line,
pubmed-meshheading:6426470-Cell Membrane,
pubmed-meshheading:6426470-Chromatography, Gel,
pubmed-meshheading:6426470-Egtazic Acid,
pubmed-meshheading:6426470-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:6426470-Humans,
pubmed-meshheading:6426470-Lymphocytes,
pubmed-meshheading:6426470-Membrane Proteins,
pubmed-meshheading:6426470-Molecular Weight,
pubmed-meshheading:6426470-Polyethylene Glycols,
pubmed-meshheading:6426470-Swine
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pubmed:year |
1984
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pubmed:articleTitle |
Isolation and characterization of a novel 68,000-Mr Ca2+-binding protein of lymphocyte plasma membrane.
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pubmed:publicationType |
Journal Article
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