Linked Life Data

6425002

Source:http://linkedlifedata.com/resource/pubmed/id/6425002

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-6-6
pubmed:abstractText
Ninety-three strains of Pseudomonas aeruginosa, isolated from 68 patients hospitalized with respiratory tract infections, burns, urinary tract infections, and other illnesses, were examined for: 1) sensitivity to the bactericidal activity of fresh normal human serum (FHS); 2) colonial morphology; 3) serogroup designation; and 4) outer membrane protein (OMP) profile. The purpose of this study was to determine if there was any relationship between any of these microbial characteristics and the propensity of this microorganism to infect a specific clinical site or tissue. The results of this study can be summarized as follows: 1) slime-producing strains were generally more serum-sensitive than non-slime producers, although serum sensitivity was not related to slime production per se; 2) CF strains were much more serum-sensitive than non-CF strains; 3) the clinical isolation site appeared to be the predominant determinant of a strain's sensitivity to FHS; 4) the ability of P. aeruginosa to colonize/infect a specific clinical site or resist the bactericidal activity of FHS was generally unrelated to serogroup specificity; and 5) whereas the OMP profile of a particular strain does not appear to correlate with its response to the bactericidal effect of FHS, it does appear to be related to its clinical isolation site.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0732-8893
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-57
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
The serum sensitivity, colonial morphology, serogroup specificity, and outer membrane protein of Pseudomonas aeruginosa strains isolated from several clinical sites.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't