| pubmed-article:6417658 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0029016 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0086661 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0926407 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0040715 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C1522702 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0162493 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0599718 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0599813 | lld:lifeskim |
| pubmed-article:6417658 | lifeskim:mentions | umls-concept:C0599893 | lld:lifeskim |
| pubmed-article:6417658 | pubmed:issue | 22 | lld:pubmed |
| pubmed-article:6417658 | pubmed:dateCreated | 1984-1-7 | lld:pubmed |
| pubmed-article:6417658 | pubmed:abstractText | We have studied somatic cell hybrids between mouse myeloma cells and IARC-BL2 Burkitt lymphoma human cells carrying a t(8;22) chromosome translocation for the presence and expression of human immunoglobin lambda chains and for the c-myc oncogene. The results indicate that the c-myc oncogene remains on the 8q+ chromosome and that the excluded and rearranged C lambda allele translocates from chromosome 22 to this chromosome 8. As a result of the translocation, transcriptional activation of the c-myc oncogene on the rearranged chromosome 8 (8q+) occurs, while the c-myc oncogene in the normal chromosome 8 is transcriptionally silent. These findings suggest that the translocation of a rearranged immunoglobulin locus to the 3' side of an unrearranged c-myc oncogene may enhance its transcription and contribute to malignant transformation. | lld:pubmed |
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| pubmed-article:6417658 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6417658 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6417658 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6417658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6417658 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6417658 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:6417658 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:6417658 | pubmed:author | pubmed-author:NishikuraKK | lld:pubmed |
| pubmed-article:6417658 | pubmed:author | pubmed-author:CroceC MCM | lld:pubmed |
| pubmed-article:6417658 | pubmed:author | pubmed-author:NowellP CPC | lld:pubmed |
| pubmed-article:6417658 | pubmed:author | pubmed-author:FinanJJ | lld:pubmed |
| pubmed-article:6417658 | pubmed:author | pubmed-author:EriksonJJ | lld:pubmed |
| pubmed-article:6417658 | pubmed:author | pubmed-author:LenoirG MGM | lld:pubmed |
| pubmed-article:6417658 | pubmed:author | pubmed-author:ThierfelderWW | lld:pubmed |
| pubmed-article:6417658 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6417658 | pubmed:volume | 80 | lld:pubmed |
| pubmed-article:6417658 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6417658 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6417658 | pubmed:pagination | 6922-6 | lld:pubmed |
| pubmed-article:6417658 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6417658 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6417658 | pubmed:articleTitle | Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt. | lld:pubmed |
| pubmed-article:6417658 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6417658 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:6417658 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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