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pubmed:abstractText |
Using monoclonal antibodies and indirect immunofluorescence an easy, reliable, inexpensive micromethod for the quantitative analysis of fetal lymphocyte markers was developed. Monoclonal antibodies specific for identification of all peripheral T lymphocytes (OKT 3), the subclass of suppressor/cytotoxic T lymphocytes (OKT 8), and for B lymphocytes (OKla 1) were employed. This technique will permit in utero recognition of immunodeficiency states which alter the ratio of these cell types.
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