Linked Life Data

6392434

Source:http://linkedlifedata.com/resource/pubmed/id/6392434

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-1-28
pubmed:abstractText
We have demonstrated the presence of the glycoprotein T200 on the surface of human epidermal Langerhans and indeterminate cells by immunoelectron microscopy with the use of a monoclonal antibody. No other epidermal cells were positive. The presence of T200 on Langerhans cells confirms their hematopoietic origin because T200 is limited to hematopoietic cells and neoplasms. Although the function of T200 is not known, antibodies directed against T200 have been previously shown to inhibit accessory cell and natural killer cell activities. While the existence of a possible relationship between Langerhans cells and natural killer cells is unclear, Langerhans cells are important in cutaneous accessory cell functions; therefore. T200 may be important in understanding the biology of Langerhans cells and their relationship to other cells in the immune response.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-202X
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
535-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Demonstration of T200 on human Langerhans cell surface membranes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.