Linked Life Data

6383270

Source:http://linkedlifedata.com/resource/pubmed/id/6383270

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1984-9-26
pubmed:abstractText
The purpose of this study was to use vitreous fluorophotometry to evaluate the effects of glucocorticoids on capillary permeability during gram-negative septic shock. Twelve preconditioned mongrel dogs were cannulated with arterial lines and Swan-Ganz catheters for complete hemodynamic monitoring. All 12 dogs were injected with fluorescein and live Escherichia coli intravenously. Six of the 12 dogs were administered methylprednisolone at set intervals after the initiation of the E coli infusion. Vitreous fluorophotometric recordings were taken hourly. Leakage of fluorescein into the extravascular space occurred in both groups, up to several hours after E coli infusion. However, in the steroid group, the capillary permeability decreased and stabilized following the initial increase in permeability. We conclude that steroids, when administered during the development of gram-negative septic shock, may modify capillary permeability changes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0004-0010
pubmed:author
pubmed:issnType
Print
pubmed:volume
119
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1021-4
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Steroid effect on capillary permeability in gram-negative septic shock. Evaluation by vitreous fluorophotometry.
pubmed:publicationType
Journal Article