Linked Life Data

637284

Source:http://linkedlifedata.com/resource/pubmed/id/637284

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1978-5-24
pubmed:abstractText
The effect of methohexitone, fentanyl, droperidol and chloralose on the response characteristics of aortic barorecptors was studied in decerebrated cats. The conclusions rest on the analysis of the drug effect on the stimulus-response curves of individual baroceptor fibres of the aortic region relating the average discharge rate (spike/s) to the average aortic arch pressure which was altered over wide ranges by a balloon catheter located in the thoracic aorta. The stimulus response curves were shifted to higher activities by methohexitone and less obviously also by droperidol. Contrarywise, chloralose and fentanyl shifted these curves to lower activities. Thus, the first two drugs increase the afferent receptor drive and favour the development of arterial hypotension, whereas the last two decrease the afferent receptor drive and act to stabilize the arterial pressure. Interestingly, at comparable depth of anesthesia arterial blood pressure levels tend to be lower with the first kind of anaesthetics as compared with the last.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0003-2417
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
[The effect of methohexital, fentanyl, droperidol, and chloralose on the aortic baroceptor discharge of decerebrated cats (author's transl)].
pubmed:publicationType
Journal Article, English Abstract