Linked Life Data

6366163

Source:http://linkedlifedata.com/resource/pubmed/id/6366163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-4-20
pubmed:abstractText
In previous studies we have demonstrated that the reduced renal reabsorption of calcium and hypercalciuria resulting from protein consumption are associated with serum insulin levels. Arginine stimulation of insulin secretion also results in hypercalciuria. The present study was designed to test whether the calciuria associated with arginine-stimulated insulin secretion is mediated by insulin inhibition of parathyroid hormone (PTH) activity. Parathyroidectomized (PTX) and sham-operated rats were infused with physiological saline, or with 12 mmol X kg-1 X hour-1 arginine in saline at 1.2 ml/hour. Analysis of data from clearance periods 90-150 minutes after infusions commenced show that arginine infusion increased urine volume, and calcium excretion (nanograms/minute and nanograms/milliliter glomerular filtration rate), to the same extent in PTX and sham-operated animals. PTH does not, therefore, appear to be involved in the calciuretic response to amino acid infusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-3166
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
622-6
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
A comparison of amino acid-induced hypercalciuria in sham-operated and parathyroidectomized rats.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't