Linked Life Data

6362470

Source:http://linkedlifedata.com/resource/pubmed/id/6362470

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-2-24
pubmed:abstractText
Starting with a population of genetically heterogeneous mice (HS/lbg), selection for a multivariate index of the ethanol withdrawal syndrome has been initiated. The study uses within-litter selection to minimize inbreeding and includes replicate high, low, and control lines. After five generations, results indicate that selection is proceeding successfully. There is evidence of asymmetry in the selection, i.e., selection is proceeding more rapidly for signs of severe withdrawal than for mild withdrawal signs. The realized heritability after five generations of within-family selection is approximately 0.15. These selected lines should eventually prove useful in determining some of the underlying genetic, physiological, and biochemical mechanisms involved in ethanol dependence.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0145-6008
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
443-7
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Selective breeding for a multivariate index of ethanol dependence in mice: results from the first five generations.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.