Linked Life Data

6362378

Source:http://linkedlifedata.com/resource/pubmed/id/6362378

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-2-24
pubmed:abstractText
The effect of sodium-8-chlorotheophyllinate (S8CT) on transplantation immunity and on PHA-reactivity of thymocytes in transformation experiments was studied. S8CT rather stimulated first graft reaction whereas 'second set' reaction is clearly inhibited. Analogous experiments with the adoptive transfer of transplantation immunity showed comparable results. Thymocytes of S8CT treated and once grafted mice had no significant effect compared with cells from non-treated animals. In contrast, an inhibition was seen if thymocytes of twice grafted and S8CT treated mice were taken. The PHA-P reactivity of thymocytes was clearly enhanced if cell donors were grafted once and treated with S8CT. Here again, the PHA-P reactivity was inhibited if the cell donors were grafted twice and treated during second transplantation. Comparable results were obtained, when instead of transplantation animals were injected with PHA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-0546
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
The bilateral effect of theophylline on immune response mechanisms.
pubmed:publicationType
Journal Article