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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
We studied the effects of body composition and maximal aerobic power on insulin sensitivity in 23 normal-weight, healthy male subjects. Eight were weight lifters, eight were long-distance runners, and seven were untrained controls. In each subject, the percentage of body weight (BW) made up of muscle and fat tissue (% muscle and % fat, respectively), the maximal aerobic power (VO2max), and the tissue sensitivity to insulin were measured. The weight lifters were characterized by 35% higher % muscle as compared with the runners or controls (P less than 0.01). VO2max in the runners was 30-40% higher than in the weight lifters or controls (P less than 0.001). During the euglycemic clamp studies, similar steady-state plasma glucose and insulin levels were achieved in each group. When calculated per total BW, the rate of glucose metabolism (M) was virtually identical in the weight lifters (10.26 +/- 1.02 mg/kg BW/min) and the runners (10.03 +/- 0.86 mg/kg BW/min), and 4045% higher than in the controls (7.10 +/- 0.75 mg/kg BW/min, P less than 0.05). When calculated per muscle mass (Mm), only the runners had a higher than normal rate of glucose metabolism (P less than 0.02). M was directly proportional to% muscle (r = 0.54, P less than 0.01) and inversely related to % fat (r = -0.72, P less than 0.001). The multiple linear regression analysis revealed a highly significant multivariate correlation between M and the combined effect of % muscle, %fat, and VO2max (r = 0.78, P less than 0.0005).(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0012-1797
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
965-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6352382-Adipose Tissue,
pubmed-meshheading:6352382-Adult,
pubmed-meshheading:6352382-Body Composition,
pubmed-meshheading:6352382-Body Weight,
pubmed-meshheading:6352382-Glucose,
pubmed-meshheading:6352382-Humans,
pubmed-meshheading:6352382-Insulin,
pubmed-meshheading:6352382-Male,
pubmed-meshheading:6352382-Muscles,
pubmed-meshheading:6352382-Oxygen Consumption,
pubmed-meshheading:6352382-Running,
pubmed-meshheading:6352382-Weight Lifting
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pubmed:year |
1983
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pubmed:articleTitle |
Effects of body composition on insulin sensitivity.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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