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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-6-23
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pubmed:abstractText |
Conditionally lethal tubulin mutants are becoming an important tool for studying microtubule structure and function. In the filamentous fungus Aspergillus nidulans it has been possible to isolate heat-sensitive beta-tubulin mutations by isolating mutants resistant to the anti-microtubule agent benomyl and screening these mutants for heat sensitivity. It has also been possible to isolate alpha-tubulin mutations, new beta-tubulin mutations and mutations in other genes whose products are likely to interact with beta tubulin as revertants of heat-sensitive beta-tubulin mutations.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-4782
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
363-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6341617-Aspergillus nidulans,
pubmed-meshheading:6341617-Hot Temperature,
pubmed-meshheading:6341617-Microtubule-Associated Proteins,
pubmed-meshheading:6341617-Microtubules,
pubmed-meshheading:6341617-Mutation,
pubmed-meshheading:6341617-Proteins,
pubmed-meshheading:6341617-Suppression, Genetic,
pubmed-meshheading:6341617-Tubulin
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pubmed:year |
1983
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pubmed:articleTitle |
Conditionally lethal tubulin mutations of Aspergillus nidulans.
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pubmed:publicationType |
Journal Article
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