Linked Life Data

6336863

Source:http://linkedlifedata.com/resource/pubmed/id/6336863

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Pt 2
pubmed:dateCreated
1983-2-25
pubmed:abstractText
Metronidazole was the most effective antianaerobic agent tested in an in vitro system that used a high-density inoculum of mixed enteric organisms. A prospective randomized clinical trial assessing metronidazole and neomycin against erythromycin and neomycin as preoperative bowel preparations demonstrated a marked reduction in the anaerobic flora of patients receiving metronidazole. A second trial revealed that intravenous metronidazole administered 1 hour before and at 8 and 16 hours after the operation provided similar protection against wound infection. Our total experience with 181 patients receiving metronidazole either by mouth or intravenously was three wound infections caused by aerobic enteric organisms, as incidence of 1.6%. There was no wound infection owing to anaerobic organisms of gut origin. The residual problem was that of six wound infections resulting from Staphylococcus aureus presumed to be of skin origin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0039-6060
pubmed:author
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-200
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Metronidazole as a prophylactic agent in wound infection after colon surgery.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial