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rdf:type |
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lifeskim:mentions |
umls-concept:C0009219,
umls-concept:C0017337,
umls-concept:C0033684,
umls-concept:C0043393,
umls-concept:C0162326,
umls-concept:C0456205,
umls-concept:C0521447,
umls-concept:C0815040,
umls-concept:C1176474,
umls-concept:C1550605,
umls-concept:C1711351
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pubmed:issue |
5
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pubmed:dateCreated |
1984-8-7
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pubmed:databankReference |
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pubmed:abstractText |
We have determined the DNA sequence of the nuclear gene coding for the 17-kd subunit VI of the ubiquinol-cytochrome c reductase. The reading frame found encodes a putative polypeptide of 17 394 daltons. This protein is highly unusual: 38% of its residues are acidic and 14% are basic amino acids. The most notable feature in the protein sequence is a stretch of 25 consecutive acidic amino acids. The polypeptide has homology with the 9-kd so-called 'hinge' protein of beef-heart complex III, which also has a cluster of acidic residues. Acidic amino acids are likely to be essential for the function of these proteins, since their degree of conservation is higher than that of other residues.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-1005115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-1195397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-178651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-200545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-222467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-364941,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-4287711,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6113054,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6126477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6159641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6259625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6260092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6260957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6272763,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6280875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6281737,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6290493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6294090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6299897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6303064,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6305514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6305819,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6311535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6319130,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-6329691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-7002730,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-7301588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-73185,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-7318825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6329732-922889
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0261-4189
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1039-43
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6329732-Amino Acid Sequence,
pubmed-meshheading:6329732-Base Sequence,
pubmed-meshheading:6329732-Cell Nucleus,
pubmed-meshheading:6329732-DNA, Fungal,
pubmed-meshheading:6329732-DNA Restriction Enzymes,
pubmed-meshheading:6329732-Electron Transport Complex III,
pubmed-meshheading:6329732-Genes,
pubmed-meshheading:6329732-Genes, Fungal,
pubmed-meshheading:6329732-Macromolecular Substances,
pubmed-meshheading:6329732-Molecular Weight,
pubmed-meshheading:6329732-Multienzyme Complexes,
pubmed-meshheading:6329732-NADH, NADPH Oxidoreductases,
pubmed-meshheading:6329732-Plasmids,
pubmed-meshheading:6329732-Quinone Reductases,
pubmed-meshheading:6329732-Saccharomyces cerevisiae
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pubmed:year |
1984
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pubmed:articleTitle |
The DNA sequence of the nuclear gene coding for the 17-kd subunit VI of the yeast ubiquinol-cytochrome c reductase: a protein with an extremely high content of acidic amino acids.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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