Linked Life Data

6327539

Source:http://linkedlifedata.com/resource/pubmed/id/6327539

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-7-3
pubmed:abstractText
Lymphocytes from Epstein-Barr virus (EBV) seronegative donors were either stimulated with Protein A or infected with EBV and cultured in growth medium containing a range of calcium levels (700 microM to less than 2 microM available calcium). Three calcium end-points for the proliferation of B lymphocytes were defined: 18 microM for mitogenically-stimulated B cells; 8 microM for a pre-12 h event in EBV transformation and less than 2 microM for a post-12 h event in EBV transformation resembling the end-point for the emergent lymphoblastoid cell line. EBV-infected lymphocytes cultured in calcium-depleted medium expressed the EB virus nuclear antigen and proliferated after addition of calcium chloride. The present study should be useful both in defining the sequence of events in EBV transformation and in studying properties specific to the transformed phenotype.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0020-7136
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
587-90
pubmed:dateRevised
2007-7-24
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Calcium concentration defines two stages in transformation of lymphocytes by Epstein-Barr virus.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't