Linked Life Data

6326957

Source:http://linkedlifedata.com/resource/pubmed/id/6326957

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-7-16
pubmed:abstractText
The anterior hypothalamus has been implicated in the higher centre control of blood pressure and more recently in hydromineral balance regulation. Using a glass recording electrode with and without a 7-barrelled iontophoretic electrode we investigated this region for blood pressure-sensitive cells. We used a ventral approach through the optic chiasma. We found 36 cells out of 91 tested that increased their firing rate in response to a spontaneous or induced decrease in blood pressure. Of these 19 increased firing in response to angiotensin II (AII) injected into the lateral cerebral ventricle and 10 of these increased firing in response to local iontophoretic application of AII. Cells responsive to an increase in blood pressure were never found. Thus cells in this area respond to hypovolaemia and hypotension as well as to AII, which could link this area with higher centre responsiveness to stimuli of extracellular thirst.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
299
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Electrophysiological investigation of cells in the region of the anterior hypothalamus firing in relation to blood pressure and volaemic changes.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't