Linked Life Data

6324950

Source:http://linkedlifedata.com/resource/pubmed/id/6324950

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-6-7
pubmed:abstractText
Fast B neurons in bullfrog sympathetic ganglia were voltage clamped with two microelectrodes. Acetylcholine (ACh) was applied onto the soma membrane by iontophoresis. A rapid nicotinic inward current was followed by a slow muscarinic inward current. After an addition of scopolamine to Ringer solution so as to block the muscarinic current, the nicotinic inward current was found to be followed by an outward current lasting for several hundred ms. It disappeared when the preceding nicotinic inward current was blocked by (+)-tubocurarine. The ACh-induced outward current was due to calcium entry through ACh-channels and subsequent opening of potassium channels. This may indicate that a rapid excitatory transmission leads to non-synaptic autoinhibition. The interaction between the calcium-dependent potassium conductance and the muscarinic action of ACh is proposed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
295
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
364-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Calcium entry through acetylcholine-channels can activate potassium conductance in bullfrog sympathetic neurons.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't