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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-5-11
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pubmed:abstractText |
Fasting duodenal juice and saliva were obtained from 26 peptic ulcer patients and 28 controls. IgA antibodies to herpes simplex virus type 1 (HSV-1) were measured by the indirect enzyme-linked immunosorbent assay (ELISA). Total IgA in the samples was measured by the double-sandwich ELISA. The median and interquartile range of anti HSV-1 IgA titres in saliva were 8 (4-12) and 4 (1-8) in ulcer patients and controls, respectively (p less than 0.02). Comparative values in duodenal juice were 12 (2-16) and 4 (0-6) (p less than 0.002). The concentration of total IgA was not higher in ulcer patients than in controls, and no correlation existed between total IgA and anti HSV-1 titres. The results add further evidence that HSV type 1 is involved in the pathogenesis of peptic ulceration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0036-5521
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
81-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6324333-Adult,
pubmed-meshheading:6324333-Aged,
pubmed-meshheading:6324333-Antibodies, Viral,
pubmed-meshheading:6324333-Duodenal Ulcer,
pubmed-meshheading:6324333-Duodenum,
pubmed-meshheading:6324333-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:6324333-Female,
pubmed-meshheading:6324333-Humans,
pubmed-meshheading:6324333-Immunoglobulin A,
pubmed-meshheading:6324333-Immunoglobulin A, Secretory,
pubmed-meshheading:6324333-Intestinal Secretions,
pubmed-meshheading:6324333-Male,
pubmed-meshheading:6324333-Middle Aged,
pubmed-meshheading:6324333-Saliva,
pubmed-meshheading:6324333-Simplexvirus
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pubmed:year |
1984
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pubmed:articleTitle |
IgA antibodies to herpes simplex virus type 1 in duodenal juice and saliva from patients with peptic ulcer and non-ulcer controls.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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