Linked Life Data

6318162

Source:http://linkedlifedata.com/resource/pubmed/id/6318162

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-2-15
pubmed:abstractText
Male Wistar rat pups received subcutaneous injections of either 100 mg/kg 6-hydroxydopamine (6-OHDA) or saline on days 1, 3, 5 and 7. The noradrenaline (NA) content of the cerebral cortex was reduced by 70% while sleep registration during the first two weeks of life did not show any significant differences between drug- and saline-treated animals. After weaning (day 25), both 6-OHDA- and saline-injected animals were reared under standard and enriched environmental conditions. Whereas a clear increase in cerebral cortical weight after experience with an enriched environment was found in saline-treated rats, 6-OHDA-treated animals had lower cortical weights and showed less increase due to the environment. These results demonstrate that catecholamine neurotransmission during early development influences the development and plasticity of the cerebral cortex.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Impaired growth of the cerebral cortex of rats treated neonatally with 6-hydroxydopamine under different environmental conditions.
pubmed:publicationType
Journal Article