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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
The paper reports a simple, sensitive and time-saving procedure for the assay of the function of the phagocytes on microsamples of whole blood. The method consists in the evaluation of the stimulation of superoxide anion (O-2) production (as superoxide dismutase-sensitive cytochrome c reduction) by leukocytes in whole blood challenged with (a) phagocytosable particles (opsonized zymosan); (b) particles that become phagocytosable by virtue of the opsonizing capacity of the plasma of blood samples (zymosan); and (c) a soluble agent such as phorbol myristate acetate. Preliminary studies indicate that this procedure can be used as a routine test because it enables information to be obtained about the respiratory responsiveness of phagocytes and about cellular and humoral defects of phagocytosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0014-2972
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
363-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6311564-Female,
pubmed-meshheading:6311564-Granulocytes,
pubmed-meshheading:6311564-Granulomatous Disease, Chronic,
pubmed-meshheading:6311564-Humans,
pubmed-meshheading:6311564-Male,
pubmed-meshheading:6311564-Opsonin Proteins,
pubmed-meshheading:6311564-Phagocytosis,
pubmed-meshheading:6311564-Superoxides,
pubmed-meshheading:6311564-Tetradecanoylphorbol Acetate,
pubmed-meshheading:6311564-Zymosan
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pubmed:year |
1983
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pubmed:articleTitle |
The measurement of superoxide anion production by granulocytes In whole blood. A clinical test for the evaluation of phagocyte function and serum opsonic capacity.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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