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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1983-9-9
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pubmed:abstractText |
Treatment of cultured epidermal cells with the tumor promoter, phorbol myristate acetate (PMA), results in a 75% inhibition of the normal isoproterenol stimulated 7-fold increase in cAMP accumulation. Maximum inhibition occurred 3 h after PMA treatment. The effect of phorbol ester on the beta-adrenergic system in mouse epidermis thus appears to be due to its action on the epidermal cell membrane and does not require mediation by macrophages.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0143-3334
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
939-40
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6307541-Animals,
pubmed-meshheading:6307541-Animals, Newborn,
pubmed-meshheading:6307541-Cells, Cultured,
pubmed-meshheading:6307541-Cyclic AMP,
pubmed-meshheading:6307541-Isoproterenol,
pubmed-meshheading:6307541-Mice,
pubmed-meshheading:6307541-Mice, Inbred C57BL,
pubmed-meshheading:6307541-Phorbols,
pubmed-meshheading:6307541-Receptors, Adrenergic,
pubmed-meshheading:6307541-Receptors, Adrenergic, beta,
pubmed-meshheading:6307541-Skin,
pubmed-meshheading:6307541-Skin Physiological Phenomena,
pubmed-meshheading:6307541-Tetradecanoylphorbol Acetate
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pubmed:year |
1983
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pubmed:articleTitle |
Inhibition of beta-adrenergic response in cultured epidermal cells by phorbol myristate acetate.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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