rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1983-8-11
|
pubmed:abstractText |
A series of experiments were run to evaluate the effect of antiemetics on the acquisition and recall of a conditioned taste aversion induced by exposure to ionizing radiation or by injection of lithium chloride. Groups of male rats were exposed to 100 rad gamma radiation or 3 mEq/kg lithium chloride following consumption of a 10% sucrose solution. They were then injected with saline or with one of three antiemetics (prochlorperazine, trimethobenzamide, or cyclizine) at dose levels that have been reported to be effective in attenuating a previously acquired lithium chloride-induced taste aversion. The pretreatments with antiemetics had no effect on the acquisition or recall of either the lithium chloride- or radiation-induced taste aversion. The data suggest that antiemetics do not disrupt lithium chloride-induced taste aversions as previously reported, nor do they effect radiation-induced taste aversion learning.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0091-3057
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
629-35
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6306696-Animals,
pubmed-meshheading:6306696-Antiemetics,
pubmed-meshheading:6306696-Avoidance Learning,
pubmed-meshheading:6306696-Benzamides,
pubmed-meshheading:6306696-Chlorides,
pubmed-meshheading:6306696-Cyclizine,
pubmed-meshheading:6306696-Lithium,
pubmed-meshheading:6306696-Lithium Chloride,
pubmed-meshheading:6306696-Male,
pubmed-meshheading:6306696-Prochlorperazine,
pubmed-meshheading:6306696-Rats,
pubmed-meshheading:6306696-Rats, Inbred Strains,
pubmed-meshheading:6306696-Taste
|
pubmed:year |
1983
|
pubmed:articleTitle |
Effects of antiemetics on the acquisition and recall of radiation- and lithium chloride-induced conditioned taste aversions.
|
pubmed:publicationType |
Journal Article
|